Not so comforting news comes from scientists at the Washington University School of Medicine in St. Louis who believe that people who survive from Covid face a risk of premature death or chronic disease in subsequent years. Unfortunately, all this does not seem to be associated with the extent of the developed disease. The results of a new study. Covid and long-term complications
During the study, the researchers cataloged the numerous diseases associated with COVID-19, providing a general overview of long-term complications. Unfortunately, the surveys have provided far from optimistic results, on the contrary they have highlighted the enormous burden that this disease could bring to the world population in the coming years. The study looked at 87,000 people with COVID-19 and nearly 5 million control patients. «Our study shows that up to six months after diagnosis, the risk of death even from a mild case of COVID-19 is not trivial and increases with the severity of the disease. It is no exaggeration to say that long-term COVID-19 – the long-term health consequences of COVID-19 – is America’s next major health crisis. Given that more than 30 million Americans have been infected with this virus, and the burden of long COVID-19 is substantial, the persistent effects of this disease will reverberate for many years and even decades. Doctors need to be vigilant in evaluating people who have contracted COVID-19. These patients will need integrated, multidisciplinary care, ”explains Ziyad Al-Aly, MD, assistant professor of medicine.Long Covid, from heart problems to hair loss. Anything that can cause
Scientists have hinted at the wide-ranging side effects that develop in COVID-19 survivors, which range from respiratory problems to irregular heart rhythms to mental health to milder ones like hair loss. “This study differs from others that have looked at long COVID-19 because, instead of focusing only on neurological or cardiovascular complications, for example, we took a broad view and used the Veterans Health Administration (VHA) extensive databases to catalog all of the diseases that may be attributable to COVID-19, ”explained Al-Aly, also director of the Center for Clinical Epidemiology and head of research and education at the Veterans Affairs St. Louis Health Care System.Covid, increased risk of death in the first 30 days
Researchers showed that after surviving the initial infection (beyond the first 30 days of illness), COVID-19 survivors had a nearly 60% increased risk of death over the next six months compared to the general population. At the end of the six months, excess deaths among all COVID-19 survivors were estimated at eight people per 1,000 patients. Among patients who were ill enough to be hospitalized with COVID-19 and who survived beyond the first 30 days of illness, there were 29 excess deaths per 1,000 patients over the next six months. These subsequent deaths due to long-term complications of the infection are not necessarily recorded as deaths due to COVID-19. Regarding the total death toll from a pandemic,Covid does not only cause respiratory problems
The myth that Coronavirus is essentially a respiratory virus must be dispelled. The truth is that Covid causes damage to any organ. Evaluating 379 diagnoses of possibly COVID-19 related diseases, 380 prescribed drug classes, and 62 administered laboratory tests, the researchers identified the major newly diagnosed health problems that persisted in COVID-19 patients for at least six months and affected almost every organ and regulatory system in the body, including:
Respiratory system: persistent cough, shortness of breath, and low oxygen levels in the blood.
Nervous system: stroke, headache, memory problems and problems with the senses of taste and smell.
Mental health: anxiety, depression, sleep disturbances, and substance abuse.
Metabolism: new onset of diabetes, obesity and high cholesterol.
Cardiovascular system: acute coronary artery disease, heart failure, heart palpitations and irregular heart rhythms.
Gastrointestinal system: constipation, diarrhea and acid reflux.
Kidney: acute kidney damage and chronic kidney disease which may, in severe cases, require dialysis.
Coagulation regulation: blood clots in the legs and lungs.
Skin: rash and hair loss.
Musculoskeletal system: joint pain and muscle weakness.
General health: malaise, fatigue and anemia.
Among hospitalized patients, those who had COVID-19 fared considerably worse than those who had the flu, according to the analysis. Survivors of COVID-19 had a 50% increased risk of death compared to flu survivors, with approximately 29 excess deaths per 1,000 patients at six months. Survivors of COVID-19 also had a substantially higher risk of long-term medical problems. “Compared to influenza, COVID-19 showed a significantly higher disease burden, both in the magnitude of the risk and in the extent of involvement of the organ system. Long COVID-19 is more than a typical post-viral syndrome. The magnitude of the risk of disease and death and the extent of organ system involvement is far greater than what we see with other respiratory viruses,The more severe the disease, the greater the risk of premature death at six
months.In addition, the researchers found that the health risks of surviving COVID-19 increased with the severity of the disease, with hospitalized patients requiring intensive care more high risk of long-term complications of COVID-19 and death. “Some of these problems can get better over time – for example, shortness of breath and cough can get better – and some problems can get worse. We will continue to follow these patients to help us understand the ongoing impacts of the virus beyond the first six months after infection. We have only been in this pandemic for just over a year, so there may be consequences of the long COVID-19 that are not yet visible ».
The study was made possible thanks to funding from the United States Department of Veterans Affairs, the Institute of Public Health at Washington University, and two awards from the American Society of Nephrology and Kidney Cure Fellowship. Scientific sources
Ziyad Al-Aly, Yan Xie, Benjamin Bowe. High-dimensional characterization of post-acute sequalae of COVID-19. Nature, 2021; DOI: 10.1038 / s41586-021-03553-9
Among COVID-19 survivors, an increased risk of death, serious illness. Major study details numerous long-term effects of COVID-19, pointing to massive health burden

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